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Scientist @fredhutch, studying viruses, evolution and immunity. Collection of #COVID19 threads here: https://bedford.io/misc/twitter/

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22 threads since April 22, 2020
May 30, 2020 / 5 tweets

Yesterday, a @CDCMMWR report was published in which I along with other @seattleflustudy investigators contributed as co-authors. The @seattleflustudy data were critical to assessment of early spread of #COVID19 in Washington State and the US. https://www.cdc.gov/mmwr/volumes/69/wr/mm6922e1.htm?s_cid=mm6922e1_w 1/5

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May 25, 2020 / 18 tweets

On Feb 29, using the genetic sequence of the first community case of #COVID19 in Washington State, I made the claim that the Washington State outbreak descended directly from the Jan 15 arrival of the WA1 case with direct travel history to Wuhan. 1/18

Trevor Bedford (@trvrb):
The team at the @seattleflustudy have sequenced the genome the #COVID19 community case reported yesterday from Snohomish County, WA, and have posted the sequence publicly to https://t.co/tbVb4MAGpy. There are some enormous implications here. 1/9
https://twitter.com/trvrb/status/1233970271318503426

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May 17, 2020 / 11 tweets

I wanted to take a moment to acknowledge the amazing team that have been responsible for @nextstrain and its work during the #COVID19 crisis. 1/11

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May 15, 2020 / 7 tweets

A resident of rural Snohomish County, “Jean” had COVID-like symptoms in late Dec 2019 and has subsequently tested positive in a serological assay. This may have been COVID-19 infection, but it’s not certain (or even likely). 1/7

The Seattle Times (@seattletimes):
Did the coronavirus arrive in Washington earlier than thought? Positive antibody tests from two Snohomish County residents who said they were ill in December put the timeline in question. https://t.co/xMoTW0pVTg
https://twitter.com/seattletimes/status/1261320489231843330

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May 12, 2020 / 14 tweets

We now have enough #SARSCoV2 genomic data from different states to make some broad conclusions about how the #COVID19 epidemic has unfolded in the US. 1/14

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May 8, 2020 / 11 tweets

I’m seeing a bunch of talk about how the code behind the simulations for the March 16 @MRC_Outbreak report (https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-9-impact-of-npis-on-covid-19/) was never previously released and is not well written. This is then taken to somehow mean that the “lockdown” policy was ill-founded. 1/11

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May 6, 2020 / 12 tweets

I wanted to address the hypothesis put forward in Korber et al (https://www.biorxiv.org/content/10.1101/2020.04.29.069054v1) that the mutation in spike protein D614G causes an increase in transmissibility of SARS-CoV-2 virus. I find this hypothesis to be plausible, but far from proven. 1/16

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April 30, 2020 / 12 tweets

I know all the discussion is about a possible “2nd wave”, but I’ve found this odd given that we haven’t finished the first one. I would think quite possible that, nationally, we’re in for a scenario of a long plateau. 1/10

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April 27, 2020 / 10 tweets

Given my statement that the US has 300k - 600k new infections per day, I’ve had a bunch of responses telling me that #TestTraceIsolate is futile and we should give up on it. This thread demonstrates the benefits of reducing transmission even if suppression is not attainable. 1/9

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April 25, 2020 / 9 tweets

If we’re going to manage a #TestTraceIsolate solution to the #COVID19 epidemic, we need a massive scale up in testing. There are some really exciting initiatives here. 1/9

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