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Assistant Professor of Biostatistics at @UF specializing in emerging infectious diseases and vaccine study design. @HarvardBiostats PhD. Tweets my own. She/her.

Jun 16, 2020 7:50 PM
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Indeed an adaptive platform treatment trial in the US was the plan. The language is visible in the clinical trials registration. But was anyone in the trial randomized to anything besides remdesivir? Anyone know the status? https://clinicaltrials.gov/ct2/show/NCT04280705

Vinay Prasad (@VPrasadMDMPH):
In the US, had we committed to running multiarm randomized trials, we would have beaten the UK in answering the steroid question by weeks (Due to the larger sample size), saving many more lives

The next @Plenary_Session will be a hot take
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My late February tweet on the topic and our NEJM paper on conducting randomized trials during outbreaks. https://www.nejm.org/doi/full/10.1056/NEJMsb1905390 ?s=20

Natalie E. Dean, PhD (@nataliexdean):
First #coronavirus treatment trial launches in the US. Starting at the University of Nebraska Medical Center where thirteen patients from the Diamond Princess cruise ship are being treated, the trial will expand to up to 50 sites globally under the same master protocol. https://t.co/3iLfhTeMru